Monoclonal Anti-Ly6g-FITC antibody produced in rat

NA.41

The rat monoclonal antibody RB6-8C5 detects Ly6G component of Gr-1 antigen, a commonly used surface marker of neutrophils.
Lymphocyte antigen 6 complex, locus G (Ly6G) is a 25kDa glycosylphosphatidylinositol (GPI)–anchored protein. It is encoded by the gene mapped to mouse chromosome 15. The encoded protein belongs to the Ly6/urokinase plasminogen activator receptor (uPAR) family. Ly6G is characterized with a “3 finger fold” motif stabilized by 4-5 disulfide bonds. Ly6G is expressed only in mice.

Murine granulocytes

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 1 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

The protein folds of lymphocyte antigen 6 complex, locus G (Ly6G) help to form a docking site for other molecules. Ly6G functions as a marker for neutrophils. The encoded protein might be implicated in the modulation of leukocyte migration.

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Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.

rat

FITC conjugate

purified immunoglobulin

primary antibodies

RB6-8C5, monoclonal

buffered aqueous solution

mouse

1 mg/mL

flow cytometry: suitable

IgG2b

XM_001475753.2

P35461

wet ice

2-8℃

mouse ... Ly6g(546644)

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12 - Non Combustible Liquids