Monoclonal Anti-KRT18-FITC antibody produced in mouse

NA.41

Keratin 18/cytokeratin 18 (CK18) is a structural protein. It is present in single-layer epithelia. It is located on human chromosome 12q13.
The antibody DC-10 reacts with Cytokeratin 18 (45 kDa). Cytokeratins are a member of intermediate filaments subfamily represented in epithelial tissues.

Human breast carcinoma cell line PMC-42

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 5-10 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Keratins help to maintain the structural integrity. They also control Fas‐mediated apoptosis and regulate cell size and protein synthesis. Keratin 18 plays a major role in the development of lung cancer. It acts as a therapeutic target for non-small cell lung cancer (NSCLC).

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Solution in phosphate buffered saline containing 15 mM sodium azide and 0.2% high-grade protease free BSA as a stabilizing agent.

mouse

FITC conjugate

purified immunoglobulin

primary antibodies

DC-10, monoclonal

buffered aqueous solution

human

0.1 mg/mL

flow cytometry: suitable

IgG1

NM_000224.2

P05783

wet ice

2-8℃

human ... KRT18(3875)

12 - Non Combustible Liquids

WGK 2