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Monoclonal Anti-Interleukin-2 antibody produced in mouse
产品编号: | 3147048 |
规格: | clone 5355, purified immunoglobulin, lyophilized powder |
包装规格: | 500 μG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-Interleukin-2 antibody produced in mouse
Anti-TCGF
Anti-IL2
Anti-lymphokine
基本信息
NACRES | NA.41 |
Immunogen【免疫原】 | purified, E. coli-derived recombinant human interleukin-2. |
Biochem/physiol Actions【生化/生理作用】 | Interleukin-2 (IL-2) is a cytokine produced by activated T cells in response to antigen stimulation. IL-2 is important for proliferation of lymphocytes, natural killer cells and macrophages and in the differentiation of CD4+ cells into Th1 and Th2 effector cells. The effects of IL-2 are mediated by the signaling activated by its binding to IL-2 receptor (IL-2 R). IL-2 activates key signaling pathways such as MAPK, JAK/STAT as well as PI3K/Akt. Activation of these pathways modulates production of inflammatory cytokines, survival and progression through cell cycle. |
Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates. |
产品性质
Quality Level【质量水平】 | 100 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 5355, monoclonal |
form【形式】 | lyophilized powder |
species reactivity | human |
technique(s) | capture ELISA: 2-8 μg/mL immunohistochemistry: 8-25 μg/mL |
isotype【同位素/亚型】 | IgG2a |
UniProt accession no.【UniProt登记号】 | P60568 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... IL2(3558) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 1 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |