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抗-白介素1单克隆抗体β 小鼠抗
Monoclonal Anti-Interleukin-1β antibody produced in mouse
产品编号: | 3147046 |
规格: | clone 8516.311, purified immunoglobulin, lyophilized powder |
包装规格: | 0.5 MG |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
抗-白介素1单克隆抗体β 小鼠抗
Monoclonal Anti-Interleukin-1β antibody produced in mouse
Anti-IL-1β
基本信息
MDL number | MFCD00162514 |
NACRES | NA.41 |
Specificity【特异性】 | The antibody will neutralize the biological activity of recombinant human IL-1β. It will not neutralize the activity of recombinant human IL-α, recombinant mouse IL-1α, or recombinant mouse IL-1β. When immobilized on a microplate, this antibody will capture both recombinant as well as natural human IL-1β. In immunoblotting, the antibody shows ~25% cross-reactivity with recombinant rat IL-1β and <5% cross-reactivity with recombinant mouse IL-1β and recombinant porcine IL-1β. Additionally, in immunoblotting, the antibody exhibits no cross-reactivity with recombinant mouse IL-α, recombinant human IL-1ra, recombinant mouse IL-1ra, or recombinant rat IL-1α. |
Immunogen【免疫原】 | purifed, E. coli-derived, recombinant human IL-1β. |
Application【应用】 | May used in immunoblotting, immunohistochemistry, ELISA, and neutralization assays |
Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
Preparation Note【制备说明】 | Monoclonal Anti-Interleukin-1(IL-1) (mouse IgG1 isotype) is purified from a mouse hybridoma utilizing Protein A affinity chromatography. |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | 8516.311, monoclonal |
form【形式】 | lyophilized powder |
species reactivity | human |
technique(s) | flow cytometry: suitable immunohistochemistry: 8-25 μg/mL using human PBMC′s neutralization: suitable western blot: 1 μg/mL |
isotype【同位素/亚型】 | IgG1 |
UniProt accession no.【UniProt登记号】 | P01584 |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... IL1B(3553) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |