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Monoclonal Anti-Interleukin-1α/Interleukin-1F1 antibody produced in rat
| 产品编号： | 3147045 |
| 规格： | clone 40508, purified immunoglobulin, lyophilized powder |
| 包装规格： | 500 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-Interleukin-1α/Interleukin-1F1 antibody produced in rat
Anti-IL1A
基本信息
| MDL number | MFCD00162513 |
| NACRES | NA.41 |
| Immunogen【免疫原】 | purified, E. coli-derived recombinant mouse interleukin-1α/interleukin-1F1. |
| Biochem/physiol Actions【生化/生理作用】 | Interleukins are proinflammatory cytokines produced on cell injury or trauma. There are two closely related types of interleukins produced by the cell, IL-1α and IL-1β that are produced in response to bacterial infection or LPS. Both IL-1α and IL-1β exert their cellular effects by signaling through IL-1 receptor type 1. The effects of IL-1α are mediated by activation of NF-κB, JNK and MAPK pathways that activated the genes in response to infection and inflammation. Overproduction of IL-1α has been implicated in inflammatory disorders like rheumatoid arthritis and periodontitis. |
| Physical form【外形】 | Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose. |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | rat |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 40508, monoclonal |
| form【形式】 | lyophilized powder |
| species reactivity | mouse |
| technique(s) | capture ELISA: 2 μg/mL neutralization: suitable |
| UniProt accession no.【UniProt登记号】 | P01582 |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | mouse ... Il1a(16175) |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 1 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
