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Monoclonal Anti-IBRDC2 antibody produced in mouse
| 产品编号： | 3146762 |
| 规格： | clone 4F1, purified immunoglobulin, buffered aqueous solution |
| 包装规格： | 100 μG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品别名
Monoclonal Anti-IBRDC2 antibody produced in mouse
Anti-IBR domain containing 2
Anti-MGC71786
Anti-KIAA0161
Anti-bA528A10.3
Anti-p53RFP
基本信息
| NACRES | NA.41 |
| General description【一般描述】 | IBR domain containing 2 (IBRDC2) is also known as ring finger protein 144B (RNF144B). It is an E3 ubiquitin ligase which is expressed in the ovaries, testis and spleen. The 303 amino acid protein is localized to the mitochondria, Golgi apparatus, cell membrane and cytoplasm. The gene encoding it is located on human chromosome 6p22.3. |
| Immunogen【免疫原】 | IBRDC2 (NP_877434, 1 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MGSAGRLHYLAMTAENPTPGDLAPAPLITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTLQEAEIACLVPVDQF |
| Biochem/physiol Actions【生化/生理作用】 | IBR domain containing 2 (IBRDC2) modulates the expression of the pro-apoptotic protein, Bax. It has a regulatory role in epithelial homeostasis and is involved in the stimulation of p53-dependent apoptosis. |
| Physical form【外形】 | Solution in phosphate buffered saline, pH 7.4 |
| Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | purified immunoglobulin |
| antibody product type | primary antibodies |
| clone【克隆】 | 4F1, monoclonal |
| form【形式】 | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable indirect immunofluorescence: suitable western blot: 1-5 μg/mL |
| isotype【同位素/亚型】 | IgG2aκ |
| GenBank® accession no. | NM_182757 |
| UniProt accession no.【UniProt登记号】 | Q7Z419 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... RNF144B(255488) |
产品说明
| Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| WGK | nwg |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
