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Monoclonal Anti-HSD11B1 antibody produced in mouse
产品别名
Monoclonal Anti-HSD11B1 antibody produced in mouse
Anti-11DH
Anti-HDL
Anti-HSD11B
Anti-11betaHSD1
Anti-MGC13539
Anti-HSD11L
Anti-HSD11
Anti-hydroxysteroid (11-beta) dehydrogenase 1
基本信息
| MDL number | MFCD08064405 |
| NACRES | NA.41 |
| General description【一般描述】 | The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. (provided by RefSeq) |
| Immunogen【免疫原】 | HSD11B1 (AAH12593, 1 a.a. ~ 292 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. Sequence MAFMKKYLLPILGLFMAYYYYSANEEFRPEMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSYVVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVNVSITLCVLGLIDTETAMKAVSGIVHMQAAPKEECALEIIKGGALRQEEVYYDSSLWTTLLIRNPCRKILEFLYSTSYNMDRFINK |
| Physical form【外形】 | Solution |
| Legal Information【法律信息】 | GenBank is a registered trademark of United States Department of Health and Human Services |
产品性质
| Quality Level【质量水平】 | 100 |
| biological source【生物来源】 | mouse |
| conjugate【偶联物】 | unconjugated |
| antibody form【抗体形式】 | ascites fluid |
| antibody product type | primary antibodies |
| clone【克隆】 | 2C10, monoclonal |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable western blot: 1:500-1:1000 |
| isotype【同位素/亚型】 | IgMκ |
| GenBank® accession no. | BC012593 |
| UniProt accession no.【UniProt登记号】 | P28845 |
| shipped in【运输】 | dry ice |
| storage temp.【储存温度】 | −20℃ |
| Gene Information | human ... HSD11B1(3290) |
安全信息
| Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |
