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Monoclonal Anti-Cul7 小鼠抗
Anti-Cul7 antibody, Mouse monoclonal
产品编号: | 3143756 |
规格: | clone Ab38, purified from hybridoma cell culture |
包装规格: | 100 μL |
产品类别: | 进口试剂 |
品牌: | Sigma-Aldrich |
优惠价: | 立即咨询 |
产品别名
Monoclonal Anti-Cul7 小鼠抗
Anti-Cul7 antibody, Mouse monoclonal
Anti-KIAA007
Anti-Cullin 7
基本信息
MDL number | MFCD09265422 |
NACRES | NA.41 |
General description【一般描述】 | Monoclonal Anti-Cul7 (mouse IgG2b isotype) is derived from the hybridoma Ab38 produced by the fusion of mouse myeloma cells (P3X63Ag8.653) and splenocytes from BALB/c mice immunized with mouse Cul7. CUL7 is expressed in all tissues and cell lines except testis and small intestine. |
Immunogen【免疫原】 | mouse Cul7. |
Application【应用】 | Monoclonal Anti-Cul7 antibody produced in mouse is suitable for immunoprecipitation and western blotting at a concentration of 0.5-1μg/mL using 3T3 total cel extract. |
Biochem/physiol Actions【生化/生理作用】 | Cullin-7 (cul7) is a protein encoded by the CUL7 gene in humans. It is also referred as 3M1, KIAA0076 and dJ20C7.5. Mutation in CUL7 gene is majorly responsible for 3M syndrome (is a rare autosomal recessive disorder). CUL7 acts as a novel gene potentially involved in liver carcinogenesis associated with metabolic syndrome (MS) and its amplification may influence cell proliferation. CUL7 functions to promote cell growth through and antagonizes the function of p53. |
Physical form【外形】 | 0.01M 磷酸缓冲盐溶液,pH 7.4,含 15mM 叠氮化钠。 |
产品性质
Quality Level【质量水平】 | 200 |
biological source【生物来源】 | mouse |
conjugate【偶联物】 | unconjugated |
antibody form【抗体形式】 | purified immunoglobulin |
antibody product type | primary antibodies |
clone【克隆】 | Ab38, monoclonal |
form【形式】 | buffered aqueous solution |
mol wt【分子量】 | antigen ~180 kDa |
species reactivity | mouse, human |
concentration【浓度】 | ~2 mg/mL |
technique(s) | immunoprecipitation (IP): suitable western blot: 0.5-1 μg/mL using 3T3 total cel extract |
isotype【同位素/亚型】 | IgG2b |
UniProt accession no.【UniProt登记号】 | Q14999 |
shipped in【运输】 | dry ice |
storage temp.【储存温度】 | −20℃ |
Gene Information | human ... CUL7(9820) mouse ... Cul7(66515) |
产品说明
Disclaimer【免责声明】 | Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals. |
安全信息
Storage Class Code【储存分类代码】 | 12 - Non Combustible Liquids |
WGK | WGK 3 |
Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, multi-purpose combination respirator cartridge (US) |