Monoclonal Anti-CAMK2D antibody produced in mouse

NA.41

The gene encoding calcium/calmodulin dependent protein kinase IIδ (CAMK2D) is localized on human chromosome 4q26. The encoded protein is a member of serine/threonine protein kinase family and the Ca²⁺/calmodulin-dependent protein kinase subfamily.
The product of this gene belongs to the serine/threonine protein kinase family and to the Ca²⁺/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: α, β, γ, and δ. The product of this gene is a δ chain. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Distinct isoforms of this chain have different expression patterns

CAMK2D (AAH32784, 301 a.a. ~ 410 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
KGAILTTMLATRNFSAAKSLLKKPDGVKESTESSNTTIEDEDVKARKQEIIKVTEQLIEAINNGDFEAYTKICDPGLTAFEPEALGNLVEGMDFHRFYFENALSKSNKPI

As a subunit of the calcium/calmodulin dependent protein kinase II complex, calcium/calmodulin dependent protein kinase II complex δ (CAMK2D) modulates the functions of ion channels and Ca²⁺ handling proteins. It also regulates the phosphorylation and acetylation of histones. CAMK2D has been shown to be overexpressed in the myocardium of diabetic patients.

Solution in phosphate buffered saline, pH 7.4

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100

mouse

unconjugated

purified immunoglobulin

primary antibodies

1A8, monoclonal

buffered aqueous solution

mouse

indirect ELISA: suitable
indirect immunofluorescence: suitable
western blot: 1-5 μg/mL

IgG2bλ

BC032784

Q6PHZ2

dry ice

−20℃

human ... CAMK2D(817)

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Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)