Monoclonal Anti-BIRC5 antibody produced in mouse

NA.41

BIRC5 (Baculoviral inhibitor of apoptosis repeat-containing 5 ), also known as Survivin, is a transmembrane glycoprotein receptor encoded by the BIRC5 gene in humans. It consists of a unique cysteine-rich extracellular module, a single membrane-spanning domain, and a serine-rich (26%) cytoplasmic tail with at least 15 potential phosphorylation sites.

Purified recombinant fragment of Survivin expressed in E.coli.
Mouse monoclonal antibody raised against Survivin

Monoclonal Anti-BIRC5 antibody produced in mouse is suitable for direct ELISA (1:10,000), flow cytometry (1:200-1:400), immunohistochemistry (1:200-1:1,000), indirect immunofluorescence (1:200-1:1,000) and western blot (1:500-1:2,000).

BIRC5 (Baculoviral inhibitor of apoptosis repeat-containing 5) functions as a cell surface receptor for factor Xa. It is predicted to be a potential factor in protease-dependent cellular effector functions.It also behaves as a receptor for factor Xa during the cell surface assembly of proteolytic activities and leukocyte mitogenesis. A study reports that the expression of BIRC5 can be controlled by mRNA splicing. It is an inhibitor of apoptosis and is expressed in various malignancies.

Ascitic fluid containing 0.03% sodium azide.

100

mouse

unconjugated

ascites fluid

primary antibodies

2H5H2, monoclonal

human

direct ELISA: 1:10,000
western blot: 1:500-1:2,000

IgG1

wet ice

−20℃

human ... BIRC5(332)

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12 - Non Combustible Liquids

WGK 3