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L-741,626
产品别名
81226-60-0
L-741,626
(±)-3-[4-(4-Chlorophenyl)-4-hydroxypiperidinyl]methylindole
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C20H21ClN2O |
| Molecular weight | 340.85 |
| MDL number | MFCD00953632 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278529 |
| NACRES | NA.77 |
| Application【应用】 | L-741,626 has been used as selective dopamine (D2) receptor antagonist to study its effects on the uptake of dopamine in human embryonic kidney 293 (HEK293) cells. It has also been used as a D2 receptor antagonist to study its effects on thyrotropin-releasing hormone (TRH) induced prolactin release. |
| Biochem/physiol Actions【生化/生理作用】 | L-741,626 is a selective dopamine (D2) receptor antagonist. |
| Features and Benefits【特点和优势】 | This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| color【颜色】 | white to beige |
| solubility【溶解性】 | DMSO: ≥20 mg/mL ethanol: 24 mg/mL H2O: insoluble |
| storage temp.【储存温度】 | room temp |
| SMILES string | OC1(CCN(CC1)Cc2c[nH]c3ccccc23)c4ccc(Cl)cc4 |
| InChI | 1S/C20H21ClN2O/c21-17-7-5-16(6-8-17)20(24)9-11-23(12-10-20)14-15-13-22-19-4-2-1-3-18(15)19/h1-8,13,22,24H,9-12,14H2 |
| InChI key | LLBLNMUONVVVPG-UHFFFAOYSA-N |
| Gene Information | human ... DRD2(1813), DRD3(1814), DRD4(1815) |
| packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
