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L-165,041
| 产品编号： | 3103877 |
| 规格： | ≥98% (HPLC), powder |
| CAS NO： | 79558-09-1 |
| 包装规格： | 5 MG，25 MG |
| 产品类别： | 进口试剂 |
| 品牌： | Sigma-Aldrich |
| 优惠价： | 立即咨询 |
产品价格查看更多规格...
| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3103877 | 5 MG | 2360 | |||
| 3103877 | 25 MG | 8620 |
产品别名
79558-09-1
L-165,041
4-[3-(4-Acetyl-3-hydroxy-2-propylphenoxy)propoxy]phenoxy-acetic acid
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C22H26O7 |
| Molecular weight | 402.44 |
| MDL number | MFCD04974501 |
| PubChem Substance ID【PubChem化学物质编号】 | 24278477 |
| NACRES | NA.77 |
| Application【应用】 | L-165,041 has been used as a peroxisome proliferator-activated receptor β/δ (PPARβ/δ) ligand to study its influence on PPARβ/δ mediated postnatal myogenesis in C2C12 myoblasts. |
| Biochem/physiol Actions【生化/生理作用】 | L-165041 dose-dependently blocks rat vascular smooth muscle cell (VSMC) proliferation and migration by inducing the cell cycle arrest. It has the potential to treat pathological cardiovascular conditions, such as restenosis and atherosclerosis. L-165041 also effectively inhibits the progression of diabetic nephropathy. It exhibits anti-apoptosis and anti-angiogenic effects. PPARβ (PPARδ) selective agonist. |
| Features and Benefits【特点和优势】 | This compound was developed by GlaxoSmithKline. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | protect from light under inert gas |
| color【颜色】 | off-white |
| mp | 127-128 ℃ (lit.) |
| solubility【溶解性】 | DMSO: >10 mg/mL |
| originator【创始人】 | GlaxoSmithKline |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CCCc1c(O)c(ccc1OCCCOc2ccc(OCC(O)=O)cc2)C(C)=O |
| InChI | 1S/C22H26O7/c1-3-5-19-20(11-10-18(15(2)23)22(19)26)28-13-4-12-27-16-6-8-17(9-7-16)29-14-21(24)25/h6-11,26H,3-5,12-14H2,1-2H3,(H,24,25) |
| InChI key | HBBVCKCCQCQCTJ-UHFFFAOYSA-N |
| Gene Information | human ... PPARD(5467) |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
| Personal Protective Equipment【个人防护装备】 | Eyeshields, Gloves, type N95 (US) |
