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次黄嘌呤

Hypoxanthine
产品编号:3097944
规格:≥99.0%
CAS NO:68-94-0
包装规格:1 G,5 G,25 G,100 G
产品类别:进口试剂
品牌:Sigma-Aldrich
优惠价:立即咨询
产品编号包装单位单价(元)国内现货国外库存询价单
30979441 G726
30979445 G922
309794425 G1420
3097944100 G4110
产品别名

68-94-0

次黄嘌呤

Hypoxanthine

6-Hydroxypurine

6-羟基嘌呤

结构式
基本信息
Empirical Formula【经验(实验)分子式】
C5H4N4O
Molecular weight
136.11
Beilstein
5811
EC number【EC 号】
200-697-3
MDL number
MFCD00005725
PubChem Substance ID【PubChem化学物质编号】
24895850
NACRES
NA.51
Application【应用】
次黄嘌呤是一种营养添加剂,适用于细菌、寄生虫(恶性疟原虫)和动物细胞等多种细胞培养应用。 次黄嘌呤是杂交瘤技术所用选择培养基的组分。
Hypoxanthine has been used:
  • to gavage mice and to evaluate the activity of xanthine oxidase (XO) in pasteurized whole milk in vivo in potassium oxonate (PO) -induced mouse model of hyperuricemia
  • as a supplement in Iscove′s modified Dulbecco′s medium (IMDM) medium to cultivate in-vitro cell line (EL-1 cells)
  • as a pure standard for the quantification of hypoxanthine in vitreous fluid sample using high-performance liquid chromatography-ultra-violet (HPLC-UV) for the estimation of post-mortem interval
Biochem/physiol Actions【生化/生理作用】
Hypoxanthine acts as an intermediate in purine metabolism. It elicits a vital role as a 5′-base of the anticodon in a few transfer-RNAs. Though similar to guanine (Gua), it is devoid of the exocyclic amino group at C(2) position. It may be used as a substrate to study the specificity and kinetics of hypoxanthine-guanine phosphoribosyl transferases.
产品性质
Quality Level【质量水平】
300
200
biological source【生物来源】
synthetic (organic)
Assay【测定】
≥99.0%
form【形式】
powder
mp
>300 ℃ (lit.)
solubility【溶解性】
formic acid: water (2:1): 50 mg/mL, clear to slightly hazy, colorless to yellow
SMILES string
O=C1NC=Nc2nc[nH]c12
InChI
1S/C5H4N4O/c10-5-3-4(7-1-6-3)8-2-9-5/h1-2H,(H2,6,7,8,9,10)
InChI key
FDGQSTZJBFJUBT-UHFFFAOYSA-N
packaging【包装】
1, 5, 25, 100 g in poly bottle
安全信息
Storage Class Code【储存分类代码】
11 - Combustible Solids
WGK
WGK 3
Personal Protective Equipment【个人防护装备】
Eyeshields, Gloves, type N95 (US)
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