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Hispidulin
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3097028 | 5 MG | 1830 | |||
3097028 | 25 MG | 5120 |
产品别名
1447-88-7
Hispidulin
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6-methoxy-4H-1-benzopyran-4-one
4′,5,7-Trihydroxy-6-methoxyflavone
6-Methoxyapigenin
Salvitin
6-Methylscutellarein
Dinatin
Scutellarein 6-methyl ether
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C16H12 O6 |
Molecular weight | 300.26 |
MDL number | MFCD00143504 |
NACRES | NA.77 |
Application【应用】 | Hispidulin has been used as a calibration standard:
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Biochem/physiol Actions【生化/生理作用】 | Hispidulin is a bioactive flavonoid with a variety of effects including antiproliferative, antifungal, anti-inflammatory, antioxidative and antiepileptic activity. Like EGCG, hispidulin appears to activate AMPK and inhibit the PI3K/Akt/mTOR pathway. The antiepileptic activity may be due to additional activity as a benzodiazepine (BZD) receptor ligand. Hispidulin also exhibits antiosteoporotic anti-atheromatous, antispasmodic and anticancer functionality. It exhibits inhibition on α-glucosidase enzymatic activity. Hispidulin inhibits platelet aggregation and is more effective than theophylline. It also acts as a modulator of the γ-aminobutyric acid receptor (GABA) and blocks the release of glutamate synaptosomes associated with cortical neurons. |
Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥98% (HPLC) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated |
color【颜色】 | white to beige |
solubility【溶解性】 | DMSO: 20 mg/mL, clear |
storage temp.【储存温度】 | −20℃ |
SMILES string | OC1=C(OC)C(O)=C(C(C=C(C2=CC=C(O)C=C2)O3)=O)C3=C1 |
InChI | 1S/C16H12O6/c1-21-16-11(19)7-13-14(15(16)20)10(18)6-12(22-13)8-2-4-9(17)5-3-8/h2-7,17,19-20H,1H3 |
InChI key | IHFBPDAQLQOCBX-UHFFFAOYSA-N |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 11 - Combustible Solids |
WGK | WGK 3 |