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Frovatriptan succinate monohydrate
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产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
3089360 | 10 MG | 1530 | |||
3089360 | 50 MG | 4490 |
产品别名
158930-17-7
Frovatriptan succinate monohydrate
R-(+) 3-Methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole monosuccinate monohydrate
Frovatriptan succinate
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C14H17N3O · C4H6O4 · H2O |
Molecular weight | 379.41 |
MDL number | MFCD18251278 |
PubChem Substance ID【PubChem化学物质编号】 | 329825767 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | During migraine condition, frovatriptan succinate monohydrate acts on extra cerebral, intracranial arteries and prevent excessive dilation of these vessels. Frovatriptan is a serotonin 5HT-1B/1D-receptor agonist used to treat migraine. Frovatriptan has high affinity for the 5-HT(1B) and 5-HT(1D) receptors while affinity for 5-HT receptors other than 5-HT(1B/1D) is substantially lower with a pEC50 value of 8.2 for the 5-HT1B receptor, compared to a pEC50 value of 6.2 for the 5-HT7 receptor. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (HPLC) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated |
color【颜色】 | white to beige |
solubility【溶解性】 | H2O: 20 mg/mL, clear |
storage temp.【储存温度】 | 2-8℃ |
SMILES string | OC(CCC(O)=O)=O.NC(C(C=C1)=CC2=C1NC3=C2C[C@H](NC)CC3)=O.O |
InChI | 1S/C14H17N3O.C4H6O4.H2O/c1-16-9-3-5-13-11(7-9)10-6-8(14(15)18)2-4-12(10)17-13;5-3(6)1-2-4(7)8;/h2,4,6,9,16-17H,3,5,7H2,1H3,(H2,15,18);1-2H2,(H,5,6)(H,7,8);1H2/t9-;;/m1../s1 |
InChI key | CUETXFMONOSVJA-KLQYNRQASA-N |
Gene Information | human ... HTR1B(3351), HTR1D(3352) |
packaging【包装】 | 10, 50 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |