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FR-900098 monosodium salt
产品别名
73226-73-0
FR-900098 monosodium salt
(3-(Acetylhydroxyamino)propyl)-phosphonic acid
BRN 2096083
P-[3-(Acetylhydroxyamino)propyl]-phosphonic acid
结构式
基本信息
Empirical Formula【经验(实验)分子式】 | C5H11NNaO5P |
Molecular weight | 219.11 |
MDL number | MFCD17215926 |
PubChem Substance ID【PubChem化学物质编号】 | 329799770 |
NACRES | NA.77 |
Biochem/physiol Actions【生化/生理作用】 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase (DXR) is an enzyme involved in the first step in the nonmevalonate pathway for isoprenoid biosynthesis in Gram-negative, Gram-positive bacteria, plants, and the parasite causing the most virulent form of malaria, Plasmodium falciparum (Mammals produce isoprenoids via the mevalonate pathway). Inhibiton of the enzyme provides alternative to traditional antimalaria therapy. FR-900098 is twice more effective than fosmidomycin against various strains of P. falciparum in vitro and the closely related P. vinckei in mice. |
产品性质
Quality Level【质量水平】 | 100 |
Assay【测定】 | ≥97% (NMR) |
form【形式】 | powder |
storage condition【储存条件】 | desiccated protect from light |
color【颜色】 | white to light brown |
solubility【溶解性】 | H2O: ≥20 mg/mL |
storage temp.【储存温度】 | −20℃ |
SMILES string | [Na+].CC(=O)N(O)CCCP(O)([O-])=O |
InChI | 1S/C5H12NO5P.Na/c1-5(7)6(8)3-2-4-12(9,10)11;/h8H,2-4H2,1H3,(H2,9,10,11);/q;+1/p-1 |
InChI key | LCFXFDGYDKNWMD-UHFFFAOYSA-M |
packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
WGK | WGK 3 |