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氟比洛芬
Flurbiprofen
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| 产品编号 | 包装单位 | 单价(元) | 国内现货 | 国外库存 | 询价单 |
| 3088212 | 1400 |
产品别名
5104-49-4
氟比洛芬
Flurbiprofen
L-790,330
(±)-2-Fluoro-α-methyl-4-biphenylacetic acid
(±)-2-氟-α-甲基-4-联苯基乙酸
结构式
基本信息
| Linear Formula【线性分子式】 | C6H5C6H3(F)CH(CH3)CO2H |
| Molecular weight | 244.26 |
| MDL number | MFCD00079303 |
| PubChem Substance ID【PubChem化学物质编号】 | 329799649 |
| NACRES | NA.24 |
| General description【一般描述】 | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia. |
| Biochem/physiol Actions【生化/生理作用】 | Fluibiprofen is a cyclooxygenase (COX) inhibitor, which is an enzyme responsible for the conversion of arachidonic acid to prostaglandin G2 (PGG2) and PGG2 to prostaglandin H2 (PGH2) in the prostaglandin synthesis pathway. This decreases the prostaglandins which cause inflammation, pain, swelling and fever. Flurbiprofen inhibits the activity of both COX-1 and -2. The S enantiomer inhibits prostaglandin synthesis and has both anti-inflammatory and analgesic activity, while the R enantiomer does not inhibit prostaglandin synthesis and displays only analgesic activity. |
| Caution【注意】 | Please find SDS provided by EDQM here.. |
| Other Notes【其他说明】 | Sales restrictions may apply. |
产品性质
| grade【等级】 | pharmaceutical primary standard |
| manufacturer/tradename | EDQM |
| mp | 110-112 ℃ (lit.) |
| application(s) | pharmaceutical (small molecule) |
| format【格式】 | neat |
| storage temp.【储存温度】 | 2-8℃ |
| SMILES string | CC(C(O)=O)c1ccc(c(F)c1)-c2ccccc2 |
| InChI | 1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18) |
| InChI key | SYTBZMRGLBWNTM-UHFFFAOYSA-N |
| Gene Information | human ... PTGS1(5742), PTGS2(5743) |
| packaging【包装】 | Unit quantity: 50 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue. |
安全信息
| Pictograms【象形图】 | GHS06 |
| Signal word【警示用语：】 | Danger |
| Hazard Statements | H301 |
| Precautionary Statements | P301 + P310 + P330 |
| Hazard Classifications【危险分类】 | Acute Tox. 3 Oral |
| Storage Class Code【储存分类代码】 | 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects |
| WGK | WGK 3 |
