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DMPQ dihydrochloride
产品别名
1123491-15-5
DMPQ dihydrochloride
5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
结构式
基本信息
| Empirical Formula【经验(实验)分子式】 | C16H14N2O2 · 2HCl |
| Molecular weight | 339.22 |
| MDL number | MFCD02262123 |
| PubChem Substance ID【PubChem化学物质编号】 | 329825339 |
| NACRES | NA.77 |
| Biochem/physiol Actions【生化/生理作用】 | DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR?) with IC50 = 80 nM. It is > 100-fold selective over EGFR, erbB2, p56, protein kinase A and protein kinase C. |
| Features and Benefits【特点和优势】 | This compound is a featured product for Kinase Phosphatase Biology research. Click here to discover more featured Kinase Phosphatase Biology products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm. This compound is featured on the PDGFR page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here. |
产品性质
| Quality Level【质量水平】 | 100 |
| Assay【测定】 | ≥98% (HPLC) |
| form【形式】 | powder |
| storage condition【储存条件】 | desiccated |
| color【颜色】 | white to beige |
| solubility【溶解性】 | H2O: >10 mg/mL |
| storage temp.【储存温度】 | room temp |
| SMILES string | Cl.Cl.COc1cc(OC)c2cc(cnc2c1)-c3ccncc3 |
| InChI | 1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H |
| InChI key | YBBAOKYVJCNJIV-UHFFFAOYSA-N |
| packaging【包装】 | 5, 25 mg in glass bottle |
安全信息
| Pictograms【象形图】 | GHS07 |
| Signal word【警示用语：】 | Warning |
| Hazard Statements | H302 |
| Hazard Classifications【危险分类】 | Acute Tox. 4 Oral |
| Storage Class Code【储存分类代码】 | 13 - Non Combustible Solids |
| WGK | WGK 3 |
