铝试剂,ACS

It is a potent inhibitor of ribonuclease and topoisomerase II by preventing the binding of the nucleic acid to the enzyme. It stimulates tyrosine phosphorylation processes including the Jak2/STAT5 pathway in NB2 lymphoma cells, ErbB4 in neuroblastoma cells, and MAP kinases, Shc proteins, phosphatidylinositide 3-kinase and phospholipase C in PC12 cells. Aurintricarboxylic acid inhibits apoptosis in many cell types. Its neuroprotective effect, perhaps due to its ability to prevent down-regulation of Ca2+ impermeable GluR2 receptors or to its ability to inhibit calpain, a Ca2+-activated protease that is activated during apoptosis.

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents.

MFCD00040925

209-319-1

C₂₂H₂₃N₃O₉

473.44

220-225° dec.

Ambient temperatures.

Powder

Soluble in water(800g/L).

14,322

36/38
Irritating to eyes and skin.

Maximum level of impurities: Insoluble matter 0.1%, Residue after ignition 0.2%, Sensitivity to aluminum P.T.

26-37
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

GU4800000

是

 

H315-H319
Causes skin irritation.Causes serious eye irritation.

P280a-P264-P305+P351+P338-P321-P332+P313-P337+P313
Wear protective gloves and eye/face protection.Wash thoroughly after handling.IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.Specific treatment (see label).If skin irritation occurs: Get medical advice/attention.If eye irritation persists: Get medical advice/attention.